منابع مشابه
An appetite for understanding appetite
I have a sweet tooth, and I will always choose any pastry over spinach salad. I also know that many readers will share this preference. However, I am also aware that an unbalanced diet, in quantity and quality, is associated with serious health problems, including type 2 diabetes, metabolic syndrome, cardiovascular diseases, and cancer. It has therefore become a pressing question in basic and t...
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Acknowledgements Authors are indebted to Dr. Diana Quiñones Tapia for expert neuroradiological assistance during the human studies and to Mr. Javier Pérez CSIC, for careful, professional drafting of the illustrations. Abstract Hypothalamic appetite regulation is a vital homeostatic process underlying global energy balance in animals and humans, its disturbances resulting in feeding disorders wi...
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Activation of lung phagocytes, whether involving residential or recruited phagocytic cells (macrophages, monocytes, neutrophils), results in a series of products important for development of inflammatory injury of the lung. An understanding of the mechanisms of cell activation as well as how products of these activated cells interact with cellular and non-cellular targets to bring about tissue ...
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A new mechanistic model based on the formation of a phagocytic synapse explains how immune cells detect and respond to direct contact with fungal pathogens.
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The voltage-gated proton channel bears surprising resemblance to the voltage-sensing domain (S1-S4) of other voltage-gated ion channels but is a dimer with two conduction pathways. The proton channel seems designed for efficient proton extrusion from cells. In phagocytes, it facilitates the production of reactive oxygen species by NADPH oxidase.
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2011
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri3078